Holistic Treatments and Supplements

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The alternative treatments and supplements on this page do not have extensive, independent studies to support them, but are generally well tolerated and could benefit your pet with TCC. Please communicate with your Veterinarian, all supplements or alternative treatments given to your pet. Some of these supplements can interfere with other medical treatments such as chemotherapy or have their own side effects. These may seem natural but they can still harm your pet. Proceed with caution and do no harm!

Recommended brands of supplements and other helpful products can be found here.

Alternative Treatments

Most of these alternative treatments are treatments found on the internet or social media. Some people strongly believe in them including members of the TCC Facebook Groups. Please communicate with your veterinarian if you want to try one of them and research these thoroughly.


Joe Tippens’ Protocol (Fenbendazole / Panacur C)

This protocol is based on Joe Tippens’ story on how he beat late stage lung cancer by using Panacur C along with Curcumin, Vitamin E and CBD Oil. It is an amazing story but proceed with caution. There are people that have used it for their dogs with TCC in the TCC Facebook groups (search the group for Fenben or Joe Tippen to read their personal stories) . Here are some key links to learn more about it.


Low Dose Naltrexone (LDN)

Low Dose Naltrexone is an opioid antagonist that blocks the opioid receptors / endorphin receptors for a short time. Then the body feels a deficiency of endorphins and sets in an overproduction which continues for the rest of the day. Endorphins regulate cell division and the immune system. Side effects if the dose is too high include lethargy and inappetence. Must be prescribed by a veterinarian.


Tagamet & Benadryl Protocol


Cancer Diet

Most authorities agree on the following ingredients to support a dog with cancer

  • Low in simple carbohydrates (sugar) is best

  • Moderate amount of fats (especially omega-3 fatty acids)

  • Adequate amounts of highly bioavailable proteins

Dr. Gregory Ogilvie, DVM, Oncologist and Professor, spent years studying nutrition’s effect on cancer when he spent 16 years at Colorado State University. Many of the articles about a “cancer diet for pets” will reference Dr. Ogilvie’s work. Here are a few good articles:

Supplements

Some of these supplements have been shown to have an anti-tumor effect or help the immune system of your pet to fight the cancer.

A link with recommended supplement brands and other helpful products can be found here. This link is for convenience only as I have no financial interest in any of these products. Most of the products are what I used for Tigger or specific recommendations by others in the TCC Facebook Groups.


Turkey Tail Mushroom

A study out of the School of Veterinary Medicine at the University of Pennsylvania in 2012 showed that high dose Polysaccharopeptide (PSP) found in the mushroom Coriolus versicolor (Turkey Tail Mushroom) delayed the progression of metastases and produced the longest survival times reported in canine hemangiosarcoma (2).

Here is a recent article from 2020 in Dogs Naturally looking at the benefits of 5 different mushrooms including Turkey Tail to help fight cancer (3).


Chinese Herbs

Traditional Chinese Veterinary Medicine (TCVM) utilizes herbs, food and acupuncture to treat the disease pattern identified in an individual patient, taking into consideration the overall condition of the patient at that time. TCVM treatments work with the body rather than against it, and the side effects, if any, are typically mild. TCVM may be used as a stand-alone treatment or integrated with western medicine treatments for cancer patients. A few commonly used herbs for cancer are:

These herbs must be prescribed by a veterinarian educated in TCVM. To find one near you use this link.


CBD

CBD has the potential to help pets with cancer by aiding the tumor shrinking action of chemotherapy, reducing pain and inflammation, boosting the immune system, improving sleep, and increasing appetite while lessening nausea. In order to find a quality CBD oil, look for:

  • Full or Broad Spectrum CBD Oil (hemp extract without THC) contains cannabinoids in addition to CBD and terpenes

  • CO2 Extraction is best versus Solvent Extraction (unless solvent is something natural like olive oil)

  • Review the Certificate of Analysis to make sure the amount of CBD is confirmed during testing and the testing is produced by a third party.

  • Try to find an organic product

  • Confirm there are no chemical additives or preservatives

  • Check with your vet to determine if CBD interferes with your pet’s current medications (7)

Dosing CBD can be confusing. “Prior to recent studies, the generally accepted therapeutic dose range for CBD in animals has been 0.1 to 0.5 mg/kg twice daily, but dosing has been updated to 0.1 to 2 mg/kg twice daily based on now-available canine and feline data”, according to Dr. Cital, co-founder of the Veterinary Cannabis Academy (8). Always start at the low end of the range and work up slowly.

There is a veterinary cannabis organization that does phone consultations with a veterinary cannabis counselor for oncology patients. They are not affiliated with any product or brand and they are not veterinarians. I have heard good things about them through the TCC Facebook group.

A Facebook group CBD Oil for Pets should be helpful as well.


Curcumin & Golden Paste

Curcumin, one of the main ingredients in the spice, Tumeric, has been found to have anti-cancer effects and the ability to reduce inflammation. One 2012 study in rats, showed a protective effect against bladder cancer (9).

This bladder cancer study in 2014 , concluded “new compounds, such as curcumin, could be complementarily used in the clinical practice to manage the recurrences and soothe the inflammatory effect of transurethral resection or intravesical chemotherapy administration, or in combination with the chemotherapies to potentiate the antitumor effect”(10).

Curcumin, taken alone in your dog’s diet is typically not absorbed well into the bloodstream when eaten. However, if a fatty food is added such as coconut oil, olive oil or fish oil to the curcumin, it can increase the absorption. Another way to increase bioavailability is to make a mixture of Golden Paste using coconut oil, curcumin, pepper and filtered water (11).

Side effects are very uncommon, but “Curcumin causes contraction of the gallbladder so it is contraindicated if your pet has gallbladder stones or bile duct obstruction. Also use with caution in diabetic patients because it can lower blood sugar a bit. Stomach ulcers and bleeding disorders are two other situations where Curcumin is not recommended. It can occasionally cause stomach upset and might slow blood clotting. These effects are all very mild but if your pet has any of these conditions then Curcumin would not be the best choice for them”(11).


Probiotics

Based on current studies in people, physicians are studying the impact of proton pump inhibitors (PPIs) as a stomach protectant for patients using NSAIDs long term. This 2018 study, suggests that PPIs protect the upper GI tract such as the stomach, but upset the bacteria in the lower intestinal tract (12). This study from 2010, suggests probiotics protect the lower intestinal tract in people taking NSAIDs long term. Veterinarians often prescribe PPI’s to prevent injuries to the GI tract when the animal is taking an NSAID long term, generally based on human studies. Therefore, it would be reasonable to assume a probiotic would be helpful to our TCC pets (13).

  • The 2010 study on people did use specific bacteria as follows: contained 900 billion viable lyophilized bacteria consisting of four strains of Lactobacilli (L. casei, L. PlantarumL. acidophilus, L. bulgaricus), three strains of Bifidobacteria (B. longuum, B. breve and B. infantis), and one strain of Streptococcus salivaris subspecies thermophilus.


Saw Palmetto

Saw Palmetto works as an anti-inflammatory offering support for bladder control and muscle tone. Many people in the TCC Facebook group use this for their dogs and have good results. Most of the studies focus on using saw palmetto to improve prostate symptoms and show it does not help.


D-Mannose

D-Mannose is used to prevent recurrent UTI’s caused by E coli. There are no studies on dogs using
D-Mannose, but there is study from 2014 looking at women with recurrent UTI’s. D-Mannose significantly reduced the frequency of infections with minimal side effects (14).


Pumpkin

Pumpkin is a good source of fiber. Pureed pumpkin (with no added sugar or spice) can help dogs and cats with both constipation and diarrhea. Adding a tablespoon or two (in proportion to their size) to their regular meal is known to help keep them regular. It can also help dogs and cats with indigestion or upset stomachs.


 References (includes links to source documents):

  1. Groves, B., 2002. Is Cimetidine (Tagamet) A Better Cure For Cancer?. [online] Second-opinions.co.uk. Available at: <http://www.second-opinions.co.uk/cimetidine.html#.X254IT-SmUn> [Accessed 25 September 2020].

  2. Dorothy Cimino Brown, Jennifer Reetz, "Single Agent Polysaccharopeptide Delays Metastases and Improves Survival in Naturally Occurring Hemangiosarcoma", Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 384301, 8 pages, 2012. https://doi.org/10.1155/2012/384301

  3. Scott, D., 2020. Medicinal Mushrooms For Cancer In Dogs. [online] Dogs Naturally. Available at: <https://www.dogsnaturallymagazine.com/medicinal-mushrooms-for-cancer-in-dogs/> [Accessed 25 September 2020].

  4. Baumgartner, B., 2017. Stasis Breaker TCM Herbal Blend Destroys Dog Tumors. [online] PET | TAO Holistic Pet Products. Available at: <https://pettao.com/stasis-breaker-dog-tumors/> [Accessed 27 September 2020].

  5. Baumgartner, B., 2017. Wei Qi Booster Strengthens Dog Immunity - PET | TAO Holistic Pet Products. [online] PET | TAO Holistic Pet Products. Available at: <https://pettao.com/wei-qi-booster-dog-immunity/> [Accessed 27 September 2020].

  6. Dressler, D., 2019. Yunnan Baiyao For Dogs: Chinese Herb For Bleeding Dog Cancers. [online] Dog Cancer Blog. Available at: <https://www.dogcancerblog.com/articles/chinese-herb-for-bleeding-dog-cancers/> [Accessed 27 September 2020].

  7. Scott, D., 2020. Choosing The Best CBD Oil For Dogs | Dogs Naturally. [online] Dogs Naturally. Available at: <https://www.dogsnaturallymagazine.com/best-cbd-oil-for-dogs/#Q1> [Accessed 28 September 2020].

  8. Johnson, C., 2019. CBD: Forget The Legal Issues—Does It Work In Veterinary Patients?. [online] DVM 360. Available at: <https://www.dvm360.com/view/cbd-forget-legal-issues-does-it-work-veterinary-patients> [Accessed 28 September 2020].

  9. El-Mesallamy H, Salman TM, Ashmawey AM, Osama N. Evaluating the role of curcum powder as a protective factor against bladder cancer--an experimental study. Asian Pac J Cancer Prev. 2012;13(10):5287-90. doi: 10.7314/apjcp.2012.13.10.5287. PMID: 23244150.

  10. Mistretta F, Buffi NM, Lughezzani G, et al. Bladder cancer and urothelial impairment: the role of TRPV1 as potential drug targetBiomed Res Int. 2014;2014:987149. doi:10.1155/2014/987149

  11. Sieyes, K., 2016. Napa Valley Holistic Veterinary Services-Golden Paste: Turmeric For Pets. [online] Napa Valley Holistic Veterinary Services. Available at: <https://www.napaholisticvet.com/blog/2016/11/5/golden-paste-turmeric-for-pets#:~:text=Also%20known%20as%20Curcuma%20longa,positive%20effect%20on%20cancer%20cells.> [Accessed 29 September 2020].

  12. Gwee KA, Goh V, Lima G, Setia S. Coprescribing proton-pump inhibitors with nonsteroidal anti-inflammatory drugs: risks versus benefitsJ Pain Res. 2018;11:361-374. Published 2018 Feb 14. doi:10.2147/JPR.S156938

  13. Montalto M, Gallo A, Curigliano V, D'Onofrio F, Santoro L, Covino M, Dalvai S, Gasbarrini A, Gasbarrini G. Clinical trial: the effects of a probiotic mixture on non-steroidal anti-inflammatory drug enteropathy - a randomized, double-blind, cross-over, placebo-controlled study. Aliment Pharmacol Ther. 2010 Jul;32(2):209-14. doi: 10.1111/j.1365-2036.2010.04324.x. Epub 2010 Apr 7. PMID: 20384610.

  14. Kranjčec B, Papeš D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84. doi: 10.1007/s00345-013-1091-6. Epub 2013 Apr 30. PMID: 23633128.

  15. Holland, C., 2003. Dog Cancer Diet - Whole Dog Journal. [online] Whole Dog Journal. Available at: <https://www.whole-dog-journal.com/health/anti-cancer-diets-for-dogs/> [Accessed 3 November 2020].

  16. Dressler, DVM, D., 2010. The Dog Cancer Diet. [online] Cancer.landofpuregold.com. Available at: <http://cancer.landofpuregold.com/the-pdfs/DogCancerDiet.pdf> [Accessed 3 November 2020].

  17. Ogilvie, G., n.d. Nutrition And Cancer: Frontiers For Cure!. [online] Cancer.landofpuregold.com. Available at: <http://cancer.landofpuregold.com/the-pdfs/nutrition-cancer1.pdf> [Accessed 3 November 2020].

  18. Ogilvie, G., n.d. Diet And Nutrition — Canine Cancer. [online] Canine Cancer. Available at: <https://www.caninecancer.com/diet-nutrition> [Accessed 3 November 2020].

  19. Ogilvie, G., n.d. Ogilvie’S Homemade Canine Cancer Food. [online] Veterinary Oncology Consultants. Available at: <https://www.vetoncologyconsults.com/sites/default/files/Ogilvie_Homemade_Cancer_Diet.pdf> [Accessed 3 November 2020].

  20. KetoPet. 2020. Scientific Articles About Ketogenic Diet For Cancer, Epilepsy, And Disease. [online] Available at: <https://www.ketopetsanctuary.com/pages/resources> [Accessed 3 November 2020].